Company profile

Philogen is a privately-owned Swiss-Italian integrated biotechnology company founded in 1996 by the brothers Dario, Duccio, Giovanni Neri, with the initial mission to develop as products the promising human antibodies discovered by Prof. Dario Neri.

Philogen focuses on the development of new biopharmaceuticals for the treatment of angiogenesis-related disorders. Angiogenesis, i.e. the formation of new blood vessels, is a characteristic feature of many severe pathologies such as cancer, rheumatoid arthritis and age-related macular degeneration.

The company has been a pioneer in the isolation, engineering and clinical development of lead products capable of targeting angiogenesis in-vivo and has been the first in the world to demonstrate that human monoclonal antibodies, specific for a marker of angiogenesis, can efficiently and selectively target the tumor neo-vasculature both in animal models and in cancer patients.

At present, Philogen has six promising anti-cancer antibody derivatives and an antibody-derivative for the treatment of rheumatoid arthritis in clinical studies. Two registrational studies (one in Phase III and one in Phase II) are about to start .

Our Zurich-based daughter company Philochem serving as the R&D unit isolates the most promising candidate products, while in Siena (Italy) the pharmaceuticals are produced according to GMP standards and advanced to clinical trials.

Philogen is independently owned and managed, generates revenue from a diversified range of activities, has been profitable each year since 1999, has signed agreements with major pharmaceutical companies and owns a diversified portfolio of international patents.